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Arrhythmia

Heart rhythm problems (heart arrhythmias) occur when the electrical impulses that coordinate your heartbeats don't work properly, causing your heart to beat too fast, too slow or irregularly. Heart arrhythmias may feel like a fluttering or racing heart and may be harmless. However, some heart arrhythmias may cause bothersome — sometimes even life-threatening — signs and symptoms. Heart arrhythmia treatment can often control or eliminate fast, slow or irregular heartbeats. In addition, because troublesome heart arrhythmias are often made worse — or are even caused — by a weak or damaged heart, you may be able to reduce your arrhythmia risk by adopting a heart-healthy lifestyle.

What's a normal heartbeat Your heart is made up of four chambers — two upper chambers (atria) and two lower chambers (ventricles). Your heart rhythm is normally controlled by a natural pacemaker (sinus node) located in the right atrium. The sinus node produces electrical impulses that normally start each heartbeat. These impulses cause the atria muscles to contract and pump blood into the ventricles. The electrical impulses then arrive at a cluster of cells called the atrioventricular (AV) node. The AV node slows down the electrical signal before sending it to the ventricles. This slight delay allows the ventricles to fill with blood. When electrical impulses reach the muscles of the ventricles, they contract, causing them to pump blood either to the lungs or to the rest of the body. In a healthy heart, this process usually goes smoothly, resulting in a normal resting heart rate of 60 to 100 beats a minute.

Types of arrhythmias Doctors classify arrhythmias not only by where they originate (atria or ventricles) but also by the speed of heart rate they cause:

  • Tachycardia This refers to a fast heartbeat — a resting heart rate greater than 100 beats a minute.
  • Bradycardia This refers to a slow heartbeat — a resting heart rate less than 60 beats a minute.

Not all tachycardias or bradycardias mean you have heart disease. For example, during exercise it's normal to develop a fast heartbeat as the heart speeds up to provide your tissues with more oxygen-rich blood. During sleep or times of deep relaxation, it's not unusual for the heartbeat to be slower.
Tachycardias in the atria Tachycardias originating in the atria include:

  • Atrial fibrillation
  • Atrial flutter
  • Supraventricular tachycardia
  • Wolff-Parkinson-White syndrome

Tachycardias in the ventricles Tachycardias occurring in the ventricles include:

  • Ventricular tachycardia
  • Ventricular fibrillation
  • Long QT syndrome

Bradycardia — A slow heartbeat
Although a heart rate below 60 beats a minute while at rest is considered bradycardia, a low resting heart rate doesn't always signal a problem. If you're physically fit, you may have an efficient heart capable of pumping an adequate supply of blood with fewer than 60 beats a minute at rest.
In addition, certain medications used to treat other conditions, such as high blood pressure, may lower your heart rate. However, if you have a slow heart rate and your heart isn't pumping enough blood, you may have one of several bradycardias, including:

  • Sick sinus syndrome
  • Conduction block

Premature heartbeats
Although it often feels like a skipped heartbeat, a premature heartbeat is actually an extra beat. Even though you may feel an occasional premature beat, it seldom means you have a more serious problem. Still, a premature beat can trigger a longer lasting arrhythmia — especially in people with heart disease. Frequent premature beats that last for several years may lead to a weak heart.
Premature heartbeats may occur when you're resting or may sometimes be caused by stress, strenuous exercise or stimulants, such as caffeine or nicotine.

Symptoms
Arrhythmias may not cause any signs or symptoms. In fact, your doctor might find you have an arrhythmia before you do, during a routine examination. Noticeable signs and symptoms don't necessarily mean you have a serious problem, however.
Noticeable arrhythmia symptoms may include:

  • A fluttering in your chest
  • A racing heartbeat (tachycardia)
  • A slow heartbeat (bradycardia)
  • Chest pain
  • Shortness of breath

Other symptoms may include:

  • Anxiety
  • Fatigue
  • Lightheadedness or dizziness
  • Sweating
  • Fainting (syncope) or near fainting

[Heart Arrhythmia, Mayo Clinic website]

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Patient Monitoring

In medicine, monitoring is the observation of a disease, condition or one or several medical parameters over time. It can be performed by continuously measuring certain parameters by using a medical monitor (for example, by continuously measuring vital signs by a bedside monitor), and/or by repeatedly performing medical tests (such as blood glucose monitoring with a glucose meter in people with diabetes mellitus). Transmitting data from a monitor to a distant monitoring station is known as telemetry or biotelemetry.

Monitoring can be classified by the target of interest, including:

  • Cardiac monitoring, which generally refers to continuous electrocardiography with assessment of the patients condition relative to their cardiac rhythm. A small monitor worn by an ambulatory patient for this purpose is known as a Holter monitor. Cardiac monitoring can also involve cardiac output monitoring via an invasive Swan-Ganz catheter.
  • Hemodynamic monitoring, which monitors the blood pressure and blood flow within the circulatory system. Blood pressure can be measured either invasively through an inserted blood pressure transducer assembly, or noninvasively with an inflatable blood pressure cuff.
  • Respiratory monitoring, such as:
    • Pulse oximetry which involves measurement of the saturated percentage of oxygen in the blood, referred to as SpO2, and measured by an infrared finger cuff
    • Capnography, which involves CO2 measurements, referred to as EtCO2 or end-tidal carbon dioxide concentration. The respiratory rate monitored as such is called AWRR or airway respiratory rate)
    • Respiratory rate monitoring through a thoracic transducer belt, an ECG channel or via capnography
  • Neurological monitoring, such as of intracranial pressure. Also, there are special patient monitors which incorporate the monitoring of brain waves (electroencephalography), gas anesthetic concentrations, bispectral index (BIS), etc. They are usually incorporated into anesthesia machines. In neurosurgery intensive care units, brain EEG monitors have a larger multichannel capability and can monitor other physiological events, as well.
  • Blood glucose monitoring
  • Childbirth monitoring
  • Body temperature monitoring through an adhesive pad containing a thermoelectric transducer.
  • Cancer therapy monitoring through circulating tumor cells[1]

A medical monitor or physiological monitor is a medical device used for monitoring. It can consist of one or more sensors, processing components, display devices (which are sometimes in themselves called "monitors"), as well as communication links for displaying or recording the results elsewhere through a monitoring network.

The development of new techniques for monitoring is an advanced and developing field in smart medicine, biomedical-aided integrative medicinealternative medicine, self-tailored preventive medicine and predictive medicine that emphasizes monitoring of comprehensive medical data of patients, people at risk and healthy people using advanced, smart, minimally invasive  biomedical devices, biosensors, lab-on-a-chip (in the future nanomedicine[4][5] devices like nanorobots) and advanced computerized medical diagnosis and early warning tools over a short clinical interview and drug prescription.
As biomedical research, nanotechnology and nutrigenomics advances, realizing the human body's self-healing capabilities and the growing awareness of the limitations of medical interventionby chemical drugs-only approach of old school medical treatment, new researches that shows the enormous damage medications can cause,[6][7] researchers are working to fulfill the need for a comprehensive further study and personal continuous clinical monitoring of health conditions while keeping legacy medical intervention as a last resort.
In many medical problems, drugs offer temporary relief of symptoms while the root of a medical problem remains unknown without enough data of all our biological systems[8] . Our body is equipped with sub-systems for the purpose of maintaining balance and self healing functions. Intervention without sufficient data might damage those healing sub systems.[8] Monitoring medicine fills the gap to prevent diagnosis errors and can assist in future medical research by analyzing all data of many patients.

Examples and applications
Blood glucose monitoring
Stress monitoring
Serotonin biosensor
Psychiatrist-on-a-chip
Epilepsy monitoring
Toxicity monitoring

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Mobile Health

Mobile Health, or mHealth, describes the use of mobile and wireless communication technologies to improve healthcare delivery, outcomes, and research. mHealth is poised to play a larger role in engaging patients in self-care as smartphone ownership is rising …. globally. Advances in smartphone software and hardware coupled with rising availability of wearable devices have resulted in exponential growth in the health apps market. Recent estimates suggest that more than 259,000 mHealth apps are available on app stores today and account for approximately 3.2 billion downloads annually. The evidence base supporting the use of apps independently of other interventions remains quite thin, and this has led to skepticism among large medical organizations about the role apps may play in healthcare. Nevertheless, apps continue to displace older technologies in several domains, for example, by replacing dedicated communication devices for individuals with autism and replacing medical bands with medical identification built into smartphone lock screens. Barriers such as privacy concerns and lack of integration into the electronic health record have limited the impact of apps, but mHealth has enormous potential to reshape healthcare delivery in the future.
[Mobile Health, Karandeep Singh, Adam B. Landman, in Key Advances in Clinical Informatics, 2017]

Digital health, particularly wearables and other connected devices, have captured the attention of consumers, providers and payers as a way to improve health, outcomes and costs. One in five Americans now owns a wearable device and more than 76% of people say they would be interested in sharing this data with their healthcare
provider, if it would contribute to improving their care. And, 70% of people said they would share data if it would reduce their insurance premiums. This all according to a survey by iTriage. [FierceMarkets]

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Angioplasty & Stenting

Your heart' s arteries can become blocked or narrowed from a buildup of cholesterol, cells or other substances (plaque). This can reduce blood flow to your heart and cause chest discomfort. Sometimes a blood clot can suddenly form or get worse and completely block blood flow, leading to a heart attack.

Angioplasty opens blocked arteries and restores normal blood flow to your heart muscle. It is not major surgery. It is done by threading a catheter (thin tube) through a small puncture in a leg or arm artery to the heart. The blocked artery is opened by inflating a tiny balloon in it.
[Angioplasty, American Heart Association]

To open a narrowed artery, a doctor may do a procedure called a percutaneous coronary intervention (PCI) or angioplasty. In it, a balloon-tipped tube (catheter) is inserted into an artery and moved to the point of blockage. Then the balloon is inflated. This compresses the plaque and opens the narrowed spot. When the opening in the vessel has been widened, the balloon is deflated and the catheter is withdrawn. The stent stays in the artery permanently and holds it open. This improves blood flow to the heart muscle and relieves symptoms (usually chest pain).

Most angioplasty procedures are done using stents. In certain patients, stents reduce the re-narrowing that sometimes occurs after balloon angioplasty or other procedures that use catheters. Patients who have angioplasty and stents recover from these procedures much faster than patients who have coronary artery bypass surgery (CABG). They have much less discomfort, too.

There are two types of stents. Stents that are covered with drugs that help keep the blood vessel from reclosing are called drug-eluting stents. Stents not coated with drugs are called bare metal stents.

Following a stent procedure the patient will need to take one or more antiplatelet agents. These medicines keep platelets from clumping together and forming blood clots in the stent and blocking the artery. One antiplatelet agent is aspirin. A second type is called a P2Y12 inhibitor. When aspirin and a P2Y12 inhibitor are used together it is called dual antiplatelet therapy (DAPT).  
[What is Stenting, American Heart Association]

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